产品货号:
Z25281
中文名称:
RBMX抗体
英文名称:
Anti-RBMX Antibody (Center)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RBMX Antibody (Center) |
指标别名 | RNA-binding motif protein;X chromosome;Glycoprotein p43;Heterogeneous nuclear ribonucleoprotein G;hnRNP G;RNA-binding motif protein;X chromosome;N-terminally processed;RBMX;HNRPG;RBMXP1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | RBMX |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This RBMX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 262-294 amino acids from the Central region of human RBMX. |
计算分子量 | 42kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes.Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs.Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter;may thus be involved in tumor suppression.When associated with SAFB,binds to and stimulates transcription from the SREBF1 promoter.Associates with nascent mRNAs transcribed by RNA polymerase II.Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection.Can either activate or suppress exon inclusion;acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2.Represses the splicing of MAPT/Tau exon 10.Binds preferentially to single- stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation;probably binds RNA as a homodimer.Binds non-specifically to pre-mRNAs.Plays also a role in the cytoplasmic TNFR1 trafficking pathways;promotes both the IL-1- beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment. |
Uniprot ID | P38159 |
相关搜索:RBMX抗体,RBMX(Center)多抗,Anti-RBMX Antibody (Center)